Pubblicazioni Scientifiche

Randomized controlled trial on Dryland And Thermal Aquatic standardized exercise protocol for chronic venous disease (DATA study).
Menegatti E-Gianesini S.
J Vasc Surg Venous Lymphat Disord. 2021 Jan 9:S2213-333X(20)30734-4
The Effects of Thermal Water Physical Exercise in Patients with Lower Limb Chronic Venous Insufficiency Monitored by Bioimpedance Analysis.
Menegatti E – Gianesini S.
Diagnostics (Basel). 2020 Oct 31;10(11):889
Segmental saphenous ablation for chronic venous disease treatment.
Gianesini S.
Phlebology. 2021 Feb;36(1):63-69
Case-control evaluation of the impact of below 20 mmHg elastic compression stockings on lower limb volume serial variations in standardized flights.
Gianesini S.
Phlebology. 2020 Apr;35(3):199-206
State of the art on cryo-laser cryo-sclerotherapy in lower limb venous aesthetic treatment.
Miyake RK – Gianesini S.
J Vasc Surg Venous Lymphat Disord. 2020 Sep;8(5):893-895.
Volume control of the lower limb with graduated compression during different muscle pump activation conditions and the relation to limb circumference variation.
Gianesini S.
J Vasc Surg Venous Lymphat Disord. 2020 Sep;8(5):814-820.
Upper limb secondary lymphedema ultrasound mapping and characterization.
Mander A – Gianesini S.
Int Angiol. 2019 Aug;38(4):334-342. doi: 10.23736/S0392-9590.19.04176-2.
Safety and short-term efficacy of telangiectasia treatment by means of an innovative combination of 532 and 808 nm transdermal diode laser.
Crippa A, Menegatti E, Zini F, Tessari L, Taibi A, Maietti E, Gianesini S.
Phlebology. 2019 Apr 6
Lower limb volume in healthy subjects following walking with compression stockings.
Gianesini S, Mosti G, Sibilla MG, Diaz J, Raffetto J, Maietti E, Zamboni P, Menegatti E.
J Vasc Surg VL 2019 in press
Mini-invasive foam sclerotherapy assisted ligation vs surgical flush ligation for incompetent sapheno-popliteal junction treatment.
Phlebology 2019 in press
Lower limbs venous kinetics and consequent impact on drainage direction.
Gianesini S et al.
Phlebology 2018 in press
Comparison Between Duplex Ultrasound and Multigate Quality Doppler Profile Software in the Assessment of Lower Limb Perforating Vein Direction.
Gianesini S, et al.
Eur J Vasc Endovasc Surg 2018, in press
Healthy subjects lower limb volume & perceived exertion following a standardized walk with and without graduated compression. J Vasc Surg 2018
in press
Ultrasound monitoring of the jugular venous pulse during space missions: a proof of concept. Ultrasound in Medicine and Biology 2017
in press CHIVA: Theory, Practice and Outcomes. Gianesini S. Vein;7:2017.
The calendar of cytokines: Seasonal variation of circulating cytokines in chronic venous insufficiency.
Spath P, Tisato V, Gianesini S, Tessari M, Menegatti E, Manfredini R, Occhionorelli S, Secchiero P, Zamboni P.
JRSM Cardiovasc Dis. 2017 in press
High resolution M-mode evaluation of jugular vein valves in patients with neurological and neurosensory disorders. Current Neurovascular Research 2017.
in press
Ligation of the sapheno-femoral junction tributaries as risk factor for groin recurrence.
Cappelli M, Molino-Lova R, Giangrandi I, Ermini S, Gianesini S.
J Vasc Surg VL 2017, in press.
Expert opinion on hot topics in Phlebology.
Gianesini S.
Endovascular Today 2017;16:51
Lower libs kinetics and consequent impact on drainage direction.
Gianesini S, et al.
Phlebology 2016
Femoral vein valve incompetence as a risk factor for junctional recurrence.
Gianesini S, et al.
Phlebology. 2016 in press
A specifically designed aquatic exercise protocol to reduce chronic lower limb edema.
Gianesini S, Tessari M, Bacciglieri P, Malagoni AM, Menegatti E, Occhionorelli S, Basaglia N, Zamboni P.
Phleb. 2016 in press
Oscillatory flow suppression improves inflammation in chronic venous disease.
Zamboni P, Spath P, Tisato V, Tessari M, Dalla Caneva P, Menegatti E, Occhionorelli S, Gianesini S, Secchiero P.
J Surg Res. 2016 Sep;205(1):238-45.
Fixing the jugular flow reduces ventricles volume and improves brain perfusion.
Zamboni P, Menegatti E, Cittanti C, Sisini F, Gianesini S, Mascoli F, Salvi F.
J Vasc Surg: Ven & Lymph 2016 in press
Clinical applicability of assessmnet of jugular flow ove the individual cardiac cycle compared with current ultrasound methodology
Sisini F, Tessari M, Menegatti E, Vannini ME, Gianesini S, Tavoni V, Gadda G, Gambaccini M, Taibi A, Zamboni P.
Ultrasound Med Biol 2016 in press
Foam sclerotherapy safety: news from the lab.
Tessari L, Gianesini S.
Flebologia 2016;42(1):41-43.
Mini-invasive high-tie by clip apposition versus crossectomy by ligature: Long-term outcomes and review of the available therapeutic options.
Gianesini S, Menegatti E, Malagoni AM, Occhionorelli S, Zamboni P.
Phlebology 2016 in press
Autologous adipose-derived stem cells: basic science, technique, and rationale for application in ulcer and wound healing.
Zollino I., Zuolo M, Gianesini S, Pedriali M, Sibilla AG, Tessari M, Carinci F, Occhionorelli, Zamboni P
Phlebology 2016 in press
Surgical techniue for deep venous reflux supression in femoral vein deuplication.
Zamboni P, Gianesini S.
Eur J vasc Endovasc Surg 216, in press
Venous hemodynamic changes in lower limb venous disease: the UIP consensus according to scientific evidence
Franceschi C, Cappeli M , Gianesini S, Mendoza E, Ermini S, Passariello F, Zamboni P.
Int. Ang. 2016 June;35 (3):236-352
Comparison among 18 mmHg and 23 mmHg elastic stockings effect on leg volume and tiredness after golf.
Gianesini S, Tessari M, Menegatti E, Spath P, Vannini ME, Occhionorelli S, Zamboni P.
Int Angiol 2016, in press
Pelvic Congestion Syndrome: does one name fit all?
Gianesini S, Antignani PL, Tessari L.
Phlebolymphology, in press
An apparently untreatable ulcer of the face.
Borghi A, Gianesini S, Pedriali M, Stefanelli A, Mangiola G, Dalla Caneva P, Lanza G, Virgili AR, Zamboni P.
International Wound Journal. 2016 Jan 10. doi: 10.1111/iwj.12567
Histologic and sonographic features of holmium laser in chronic venous disease treatment.
Gianesini S, Gafà R, Occhionorelli S, Menegatti E, Malagoni AM, Spath P, Zamboni P.
Int. Ang. in press
Laser-assisted strategy for reflux abolition in a modified CHIVA approach
Sergio Gianesini, Erica Menegatti, Michele Zuolo, Mirko Tessari, Paolo Spath, Simona Ascanelli, Savino Occhionorelli, Paolo Zamboni
Veins&Lymphatics DOI: 10.4081/vl.2015.5246
A phlebo-lymphology humanitarian trip to Matagalpa, Nicaragua.
Gianesini S, Cavezzi A, Mosti G, Tessari L, Zini F, Urso S, Campana F, Tessari M, Della Caneva P, Espinoza F, Rocha R, Neuhardt D, Mowatt-Larssen E, Zygmunt J, Cortesi S, Morrison T, Morrison N.
Veins&Lymphatics. DOI:
Modulation of circulating cytokine-chemokine profile in patients affected by chronic venous insufficiency undergoing surgical haemodynamic correction.
Tisato V, Zauli G, Gianesini S, Menegatti E, Brunelli L, Manfredini R, Zamboni P, Secchiero P.
J Immunol Res 2014;2014:473765.
Ultrastructure of internal jugular vein defective valves.
Zamboni P., Mascoli F, Salvi F, Menegatti E, Gianesini S, Tisato V, Secchiero P.
Phlebology, 2014 Jun 27. pii:0268355514541980
CHIVA strategy in chronic venous disease treatment: instructions for users.
Gianesini S, Occhionorelli S, Menegatti E, Zuolo M, Tessari M, Spath P, Ascanelli S, Zamboni P.
Phlebology 2014 apr 22 [Epub ahead of print]
Human Internal Jugular Valve M-mode Ultrasound Characterization.
Menegatti E, Tessari M, Gianesini S, Vannini ME, Sisini F, Zamboni P.
Curr Neurovasc Res 2014;2014:473765.
Inibitory effect of natural anti-inflammatory compounds on cyrokines released by chronic venous disease patient-derived endothelial cells.
Tisato V, Zauli G, Rimondi E, Gianesini S, Brunelli L, Menegatti E, Zamboni P, Secchiero P.
Mediators Inflamm 2013;2013:423407.
Oscillatory turbulent flow in chronic venous disease induces pro-inflammatory and reparative biological signaling.
S. Gianesini, V. Tisato, Menegatti E, Volpi I., Voltan R., Occhionorelli S., Secchiero P., Zamboni P.
J Vasc Surg: venous and Lymphatic disorders 2013;1:108.
GM_CSF exhibits anti-inflammatory activity on endothelial cells derived from chronic venous disease patients.
Tisato V., Secchiero P, Rimondi E, Gianesini S, Menegatti E, Casciano F, Zamboni P, Zauli G.
Mediators of InflammationVolume 2013, Article ID 561689.
Feasibility of endovenous laser in type I CHIVA procedure: a new minimally invasive and saphenous paring therapeutic option.
Gianesini S., Menegatti E., Zuolo M., Tessari M., Ascanelli S., Occhionorelli S., Zamboni P.
Veins & Lymphatics, in press, DOI: 10.4081/1755
Endothelial PDGF-BB produced ex vivo correlates with relevant hemodynamic parameters in patients affected by chronic venous disease.
Tisato V, Zamboni P, Menegatti E, Gianesini S, Volpi I, Zauli G, Secchiero P.
Cytokine. 2013 Aug;63(2):92-6.
The omohyoid muscle entrapment of the internal jugular vein. A still unclear pathogenetic mechanism.
Gianesini S., Menegatti E., Mascoli F., Salvi F., Bastianello S., Zamboni P.
Phlebology. 2013 May 16. [Epub ahead of print]
Endothelial Cells Obtained from Patients Affected by Chronic Venous Disease Exhibit a Pro- Inflammatory Phenotype
Tisato V, Zauli G, Voltan R, Gianesini S, di Iasio MG, Volpi I, Fiorentini G, Zamboni P, Secchiero P.
PLoS ONE 2012:7(6):e39543. doi:10.1371/journal.pone.0039543
Panbacterial real-time PCR to evaluate bacterial burden in chronic wounds treated with Cutimed Sorbact TM
Gentili V, Gianesini S, Balboni PG, Menegatti E, Rotola A, Zuolo M, Caselli E, Zamboni P, Di Luca D.
Eur J Clin Microbiol Infect Dis. 2012 Jul;31(7):1523-9.
The recurrent cervical swelling sindrome
Franceschi C., Gianesini S., Bahnini A., Laurian C., Menegatti E., Zamboni P.
Phlebology, 2012 Mar;27(2):90-2.
Great saphenous varicose vein surgery without sapheno-femoral junction disconnection
Zamboni P, Gianesini S, Menegatti E, Tacconi G, Palazzo A, Liboni A.
Br J Surg. 2010 Jun;97(6):820-5.
A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency.
Zamboni P, Galeotti R, Menegatti E, Malagoni AM, Gianesini S, Bartolomei I, Mascoli F, Salvi F.
J Vasc Surg. 2009 Dec;50(6):1348-58.e1-3.
Venous collateral circulation of the extracranial cerebrospinal outflow routes.
Zamboni P., Consorti G., Galeotti R., Gianesini S., Menegatti E., Tacconi G., Carinci F.
Curr Neurovasc Res. 2009 Aug;6(3):204-12.
Echo-guided foam sclerotherapy treatment of venous malformation involving the sciatic nerve.
Gianesini S, Menegatti E, Tacconi G, Scognamillo F, Liboni A, Zamboni P.
Phlebology. 2009;24(1):46-7.
Influence of genetic polymorphism in ulcer healing process after superficial venous surgery.
D.Gemmati, S.Tognazzo, L.Catozzi, S. Carandina, M. De Palma, G. Tacconi, S. Gianesini, G.L. Scapoli, P. Zamboni.
J Vasc Surg. 2006 Sep;44(3):554-62.


Oscar MALETI, Jovan MARKOVIC, Erika MENDOZA, Javier L. MONEDERO, Gregory MONETA , Hayley MOORE, Nick MORRISON, Giovanni MOSTI, Olle NELZÉN, Alfred OBERMAYER , Tomohiro OGAWA, Kurosh PARSI, Hugo PART SCH, Fausto PASSARIELLO, Michel R. PERRIN, Paul PITTAL UGA, Seshadri RAJU, Stefano RICCI, Antonio ROSALES, Angelo SCUDERI, Carl-Erik SLAGSVOLD, Anders THURIN, Tomasz URBANEK, Andre VAN RIJ, Michael VASQUEZ, Cees H. A. WITTENS, Paolo ZAMBONI, Steven ZIMMET, Santiago Zubicoa EZPELETA
Venous hemodynamic changes in lower limb venous disease: the UIP consensus according to scientific evidence
International Angiology 2016 June;35 (3):236-352

2) International Union of Phlebology Pelvic Congestion Syndrome Guidelines 2018

3) International Union of Phlebology Sclerotherapy Guidelines 2019

4) International Union of Phlebology Venous Mapping Guidelines 2019

5) Gianesini S. Global guidelines trends and controversies in lower limb venous and lymphatic disease: Narrative literature revision and experts’ opinions following the vWINter international meeting in Phlebology, Lymphology & Aesthetics, 23-25 January 2019. Phlebology. 2019 Sep;34(1 Suppl):4-66. 


1. Pathophysiology of venous reflux
Author: S. Gianesini, P. Zamboni
Phlebology, Vein Surgery and Ultrasonography: Diagnosis and Management of Venous Disease
Springer 2013

2. Insufficienza Venosa Cronica Cerebro-Spinale
Author: P. Zamboni, P. Veroux, C. Setacci.
Co-Author: S. Gianesini, E. Menegatti
Testo di Chirurgia Vascolare
Edizioni Minerva Medica 2012

3. Chronic Cerebro-Spinal Venous Insufficiency
Author: P. Zamboni, S. Gianesini, E. Menegatti
The Oxford Textbook of Vascular Surgery
Oxford Univeristy Press 2012

4. Hemodynamic changes as a result of alternative interventions
Author: P. Zamboni, C. Franceschi
Co-Author: L. Blomgren, A. Cavezzi, E. Mendoza, M. Cappelli, S. Gianesini
Venous Hemodynamic concepts and measurements.
Consensus conference UIP 2013

5. Saphenous sparing options
Author: S. Gianesini
Tips & Tricks in Angiology.
Minerva 2016, in press

6. Phlebo-lymphedema ulcer management
Author. S. Gianesini, E. Menegatti, P. Zamboni
Lymphedema compendium
Springer 2016

7. Hemodynamics: venous and lymphatics objective assessment
Author. S. Gianesini, J. Patel
Vascular and Endovascular Controversies Update book, 2018 edition

8. Hydrotherapy for lymphedema
Author. S. Gianesini, S. Masiero, f. Lurie
Vascular and Endovascular Controversies Update book, 2018 edition

9. Foam sclerotherapy for Aesthetic Sclerotherapy
Author. S. Gianesini, L. Tessari
Sociedad Espanola de Medicina Estetica 2018 Course Textbook

10. Foam sclerotherapy for saphenous treatment
Author. S. Gianesini, L. Tessari
Sociedad Espanola de Medicina Estetica 2018 Course Textbook

11. Foam sclerotherapy
Author. S. Gianesini, L. Tessari
Nano Textbook 2018, Medea edizioni

12. Sclerotherapy state of the art
Author. S. Gianesini, L. Tessari
Updates and advances in Phlebology Textbook, Medea edition 2018

13. Chronic venous hypertension: what to do when there is no venous disease to treat
Author. S. Gianesini, Menegatti E, Baccellieri D et al.
Vascular and Endovascular Controversies Update book, 2019 edition


    1. Principles of Venous Hemodynamics
      Author: Franceschi C, Zamboni P.
      Co-Authors: De Palma M., Carandina S., Gianesini S., Menegatti E.
      Nova Biomedical 2009.
    2. Venous Hemodynamics

Zamboni P, Mendoza E, Gianesini S
Springer 2017, in press.